An initiator- and catalyst-free hydrogel coating process for 3D printed medical-grade poly(ε-caprolactone)

• Jochen Löblein,
• Thomas Lorson,
• Miriam Komma,
• Tobias Kielholz,
• Maike Windbergs,
• Paul D. Dalton and
• Robert Luxenhofer

Beilstein J. Org. Chem. 2021, 17, 2095–2101, doi:10.3762/bjoc.17.136

• surface modification, we also observe bulk polymerization, which is expected for this method, and currently limits the controllability of this procedure. Keywords: additive manufacturing; light-induced polymerization; self-initiated photografting and photopolymerization; surface-initiated polymerization

• achieved with self-initiated photografting and photopolymerization (SIPGP, Scheme 1). SIPGP is a simple, solvent-free bulk/surface photografting first introduced by Deng et al. grafting maleic anhydride [20] and styrene [21] onto low-density poly(ethylene) films. Later, this was extended for other monomers

• exposed PCL fibers in the PHEMA-filled MEW scaffolds. Schematic representation of the self-initiated photografting and photopolymerization (SIPGP) of 2-hydroxyethyl methacrylate (HEMA) including intersystem crossing from singlet to triplet state which is mandatory for the formation of a biradical (left